Early T-cell precursor acute lymphoblastic leukemia
نویسندگان
چکیده
منابع مشابه
Early T-cell Precursor Acute Lymphoblastic Leukemia/Lymphoma.
Discrete diagnostic subtypes of T lymphoblastic leukemia/lymphoma (T-cell acute lymphoblastic leukemia/lymphoma, T-ALL) have historically not been widely recognized. Recently, a novel subset with distinctive immunophenotypic, molecular, and clinical features has been proposed. Termed early T-cell precursor acute lymphoblastic leukemia (ETP-ALL), these cases seem to correspond to a very early st...
متن کاملMixed-phenotypic acute leukemia: cytochemically myeloid and phenotypically early T-cell precursor acute lymphoblastic leukemia
TO THE EDITOR: Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is characterized by the specific immunophenotype of CD1a, CD8, and CD5 with stem cell or myeloid marker expression. This leukemia presents a particular flow cytometric diagnostic challenge, as it frequently exhibits sufficient myeloid-lineage differentiation to be classified as mixed-phenotype acute leukemia (MPAL). Th...
متن کاملPrimary laryngeal manifestation in precursor T-cell acute lymphoblastic leukemia
Primary involvement of the larynx in non-Hodgkin's lymphoma (NHL) is rare. Early symptoms are non-specific and thus, it is difficult to diagnose. In the present study, the case of a 52 year-old male with hoarseness due to diffuse T-cell lymphoma as the first manifestation of precursor T-cell acute lymphoblastic leukemia is presented. Subsequent to treatment with three cycles of the etoposide an...
متن کاملPrecursor T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma and acute biphenotypic leukemias.
Session 4 of the 2005 Society of Hematopathology/European Association for Haematopathology Workshop focused on case presentations of precursor T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma (pre-T ALL/LBL) and acute biphenotypic leukemia. Pre-T ALL represents approximately 15% of childhood and 25% of adult ALL cases. Pre-T LBL comprises 85% to 90% of LBL and frequently manifests as ...
متن کاملMolecular Features of Three Children Diagnosed With Early T-Cell Precursor Acute Lymphoblastic Leukemia
Dear Editor, We describe the diagnostic characteristics of three pediatric patients with early T-cell precursor (ETP)-ALL. All three patients had hyperleukocytosis with a white blood cell (WBC) count of more than 100.0×10/L, showed immunophenotypic findings consistent with ETP-ALL, and were positive for FLT3 mutations. The clinical and laboratory findings, including immunophenotyping results (F...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2018
ISSN: 1768-3262
DOI: 10.4267/2042/69008